Zebrafish aqp0 mutant lens growth. Zebrafish standard length (A) and lens diameter (B) as a function of age (dpf) for WT, aqp0a?/?, aqp0b?/?, and double aqp0a?/?/aqp0b?/? mutants. WT and aqp0b?/? standard length growth plateaued at ?24 mm after ?350 dpf (A, red and blue); in aqp0a?/?, at ?23 mm after ?350 dpf (A, green). The double mutant standard length plateaued at ?20 mm after the age of ?180 dpf (A, black). Lens growth in WT and aqp0b?/? plateaued at ?710 µm (B, red and blue), which corresponds to ?500 dpf; there was no plateau for samples from aqp0a?/? mutants with a maximum attained value of 900 µm at 900 dpf (B, green), and lens growth plateaued at ?640 µm in double homozygotes after ?230 dpf (B, black).
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