FIGURE

Fig. 4.

ID

ZDB-FIG-210320-31

Publication

Giardoglou et al., 2021 - A Zebrafish Forward Genetic Screen Identifies an Indispensible Threonine Residue in the Kinase Domain of PRKD2

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Fig. 4.

Atrioventricular canal markers remain expressed throughout the heart in s411 mutant embryos. Ectopic expression of atrioventricular canal (AV) markers in s411 mutant embryos as shown by wholemount in situ hybridization. notch1b antisense probe in lateral (A,B) and dorsal (A′,B′) view of wild-type embryos (A,B) and s411 mutants, respectively (A′,B′), at 72 hpf. klf2a in wild-type (C) and s411 mutants (C′) and bmp4 in wild-type (D) and s411 mutants (D′) at 72 hpf. All three AV differentiation markers show restricted expression pattern in the AV and outflow tract of wild-type embryos, while they remain expressed throughout the heart in s411 mutants. n=10 in each of three independent experiments. Scale bars: 150 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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