ZFIN Image: Giardoglou et al., 2021, Fig. 4.

Image

Figure Caption

Fig. 4.

Atrioventricular canal markers remain expressed throughout the heart in s411 mutant embryos. Ectopic expression of atrioventricular canal (AV) markers in s411 mutant embryos as shown by wholemount in situ hybridization. notch1b antisense probe in lateral (A,B) and dorsal (A′,B′) view of wild-type embryos (A,B) and s411 mutants, respectively (A′,B′), at 72 hpf. klf2a in wild-type (C) and s411 mutants (C′) and bmp4 in wild-type (D) and s411 mutants (D′) at 72 hpf. All three AV differentiation markers show restricted expression pattern in the AV and outflow tract of wild-type embryos, while they remain expressed throughout the heart in s411 mutants. n=10 in each of three independent experiments. Scale bars: 150 μm.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Biol. Open