FIGURE

Fig. 9

ID

ZDB-FIG-210225-16

Publication

Balkrishna et al., 2020 - Calcio-Herbal Medicine Divya-Swasari-Vati Ameliorates SARS-CoV-2 Spike Protein-Induced Pathological Features and Inflammation in Humanized Zebrafish Model by Moderating IL-6 and TNF-α Cytokines

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Fig. 9

Figure 9 Gene expression levels of IL-6, IL-10, and TNF-α in vivo. (A) Dexamethasone and DSV at 28 µg/kg and 142 µg/kg showed highly significant (P<0.0001) reduction in the IL-6 expression levels while 6 µg/kg was significant at P<0.001. (B) IL-10 showed highly significant reduction with 142 µg/kg of DSV treatment and with dexamethasone, while the other dosages were not significant. (C) Dexamethasone showed significant (P<0.005) reduction of TNF-α levels at 4 days and P<0.0001 at 7 days. Divya-Swasari-Vati showed similar effects to the dexamethasone group, with 142 µg/kg dosage and only a slight reduction (P<0.05) with 28 µg/kg dosage after 7 days, rest of the treatments were not significant (ns). * P<0.05, ** P<0.05, *** P<0.001, **** P<0.0001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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