FIGURE

Fig. 6

ID
ZDB-FIG-210222-56
Publication
Rastogi et al., 2020 - Modulating glutathione thiol status alters pancreatic β-cell morphogenesis in the developing zebrafish (Danio rerio) embryo
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Fig. 6

Fig. 6. Nrf2a is essential for redox dependent disruption of β-cell morphology. Nrf2a wt/wt or Nrf2a m/m fish were exposed to water (n = 70 fish), 77.6 μM tBOOH (n = 32 fish) or 776 μM tBOOH (n = 35 fish) for 10 min at 48 hpf and their length (A), β-cell cluster area (B) and incidence of hypomorphic islets (cutoff represented by dashed line) (C) were measured at 96 hpf. Different letters indicate significantly different means across indicated group. p < 0.05 compared to respective control as determined by a 1-way ANOVA followed by a Tukey-Kramer post-hoc.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
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