FIGURE

Figure 1

ID

ZDB-FIG-210125-15

Publication

Moreno-Ayala et al., 2021 - Variability of an Early Developmental Cell Population Underlies Stochastic Laterality Defects

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Figure 1

Cell Number Variability during Early Embryogenesis

(A) Maximum projection of confocal images of a Tg[sox17:GFP] embryo at 75% epiboly stage showing the endoderm (red), DFCs (green), and nuclei (blue). Scale bar, 80 μm.

(B) Graphical representation of an 8-somite stage embryo, the KV, and the organ laterality at later stages.

(C–E) Cell number in endoderm (n = 49), DFCs (n = 49), and KV (n = 37), respectively, for individual embryos. The coefficient of variation (C_V) is indicated at the bottom right; (C) and (D) also show the total cell number on the x axis (C_V = 4.8%) and the coefficient of determination (R²). Total cell numbers are in good agreement with a previous publication (Kobitski et al., 2015).