FIGURE

Figure 7

ID

ZDB-FIG-201214-17

Publication

Chang et al., 2020 - Phorbol 12-Myristate 13-Acetate Induced Toxicity Study and the Role of Tangeretin in Abrogating HIF-1α-NF-κB Crosstalk In Vitro and In Vivo

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Figure 7

TAN neutralized PMA induced elevated ROS production by promoting antioxidant response. (A) Western blotting analysis of oxidative stress and inflammation markers evaluated from ear tissue homogenates, (B) Western blotting analysis of antioxidant activity markers evaluated from ear tissue homogenates, (C) Nitric oxide assay evaluated from mice ear tissue homogenates, (D) Malondialdehyde lipid peroxidation assay. Densitometry analysis of these respective proteins were normalized by β-actin and evaluated through Image J software. The data are represented as mean ± S.D. of three independent experiments * p < 0.05, ** p < 0.01, *** p < 0.001 and ns (non-significant). PMA vs. control, PMA vs. TAN 10 mg/kg and 30 mg/kg. Magnification = 200×. Statistical significance analysis was carried out through a one-way analysis of variance (ANOVA) prism.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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