ZFIN ID: ZDB-FIG-201203-4
Ren et al., 2019 - Canonical Wnt5b Signaling Directs Outlying Nkx2.5+ Mesoderm into Pacemaker Cardiomyocytes. Developmental Cell   50(6):729-743.e5 Full text @ Dev. Cell
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Condition:
Anatomical Terms:
Stage Range: 14-19 somites to 20-25 somites
PHENOTYPE:
Fish:
Condition:
Observed In:
Stage Range: 20-25 somites to Long-pec

Fig. 5 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
mCherry ia5Tg; w33Tg heat shock 20-25 somites heart primordium IFL
wnt5bta98/ta98; ia5Tg; twu277Tg control 20-25 somites heart primordium IFL
wnt5b WT control 14-19 somites anterior lateral plate mesoderm ISH
20-25 somites heart primordium ISH
fb7Tg control 14-19 somites cardiac conduction system cardiac muscle myoblast ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
co19Tg; w33Tg heat shock Long-pec cardiac conduction system cardiac muscle cell increased amount, abnormal
ia5Tg; w33Tg heat shock 20-25 somites heart primordium mCherry expression increased amount, abnormal
20-25 somites heart primordium mCherry expression increased distribution, abnormal
wnt5bta98/ta98 control Long-pec heart contraction decreased rate, abnormal
wnt5bta98/ta98; ia5Tg; twu277Tg control 20-25 somites heart primordium mCherry expression decreased amount, abnormal
20-25 somites heart primordium mCherry expression decreased distribution, abnormal
wnt5bta98/ta98; twu277Tg control Prim-5 cardiac conduction system cardiac muscle cell decreased amount, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Developmental Cell for permission to reproduce figures from this article. Please note that this material may be protected by copyright.

Reprinted from Developmental Cell, 50(6), Ren, J., Han, P., Ma, X., Farah, E.N., Bloomekatz, J., Zeng, X.I., Zhang, R., Swim, M.M., Witty, A.D., Knight, H.G., Deshpande, R., Xu, W., Yelon, D., Chen, S., Chi, N.C., Canonical Wnt5b Signaling Directs Outlying Nkx2.5+ Mesoderm into Pacemaker Cardiomyocytes, 729-743.e5, Copyright (2019) with permission from Elsevier. Full text @ Dev. Cell