FIGURE

Figure 8.

ID

ZDB-FIG-201003-232

Publication

Annunziato et al., 2020 - Chemical Characterization of a Legacy Aqueous Film-Forming Foam Sample and Developmental Toxicity in Zebrafish (Danio rerio)

Other Figures

All Figure Page

Back to All Figure Page

Figure 8.

Exocrine pancreas and endocrine pancreatic beta cell development at 96 h post fertilization (hpf) larvae with AFFF exposure. (A) The area of endocrine pancreatic beta cell islets is graphed. (B) Representative images of normal and fragmented islet morphology in 96 hpf larvae. Separate islet fragments are circled. (C) Pie charts depict the percentage of whole and fragmented beta cell islet morphologies observed. (D) The length of the exocrine pancreas normalized to larval body length is graphed. (E) Individual pancreas lengths are plotted for each treatment group. The 10th (stunted) and 1st (severely stunted) percentile marks are set by control pancreas measurements. (F) Representative images depict a normal exocrine pancreas and severely stunted pancreas in a larva exposed to 4.40×10−4% AFFF. Bars represent mean±SEM. Asterisk (*) indicate p<0.05 compared with 0% AFFF, one-way ANOVA, Tukey’s HSD post hoc test or Fisher’s Exact Test for qualitative assessments. n=6 vials per treatment group. Note: AFFF, aqueous film-forming foam; ANOVA, analysis of variance.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Environ. Health Perspect.