FIGURE

Fig. 2.

ID

ZDB-FIG-200910-19

Publication

Oppel et al., 2020 - suz12 inactivation in p53 and nf1 deficient zebrafish accelerates the onset of MPNSTs and expands the spectrum of tumor types to include adenocarcinoma, leukemia, and soft tissue sarcoma

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Fig. 2.

Tumor watch of suz12-mutant fish in the p53^m/m, nf1b^−/−, nf1a^+/⁻ andp53^m/m, nf1b^−/−, nf1a+/+ backgrounds. Representative experiments are displayed to show tumor onset time for fish with nf1a^+/− genotype (A) or nf1a^+/+ genotype (B), plotted by suz12 genotype; either three out of four (suz12^{+/−/−/−}; left), two out of four (suz12^+/+/−/−; middle), or one out of four (suz12^+/+/+/−; right) suz12 alleles are knocked out. The data from each knockout population was compared to the respective suz12-wild-type control population to calculate P-values using Student's t-tests.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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