Short-term assay of tricyclic antidepressants and RIMAs. (A–F) Treatment with amitriptyline, clomipramine, imipramine, moclobemide, pirlindole and toloxatone did not significantly decrease the percentage of zebrafish exhibiting the affected muscle phenotype detected by birefringence. Treatment with 2.5 μg/ml aminophylline significantly decreased the percentage of affected fish. Data represent means±s.e.m.; *P<0.05 versus paired control by one-way ANOVA and Bonferroni post-hoc test. Values above each column indicate the number of sapje (N) and sapje-like (n) fish treated with the respective drug.
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