FIGURE

Fig 1

ID

ZDB-FIG-200729-1

Publication

Osman et al., 2020 - Mycobacterium marinum phthiocerol dimycocerosates enhance macrophage phagosomal permeabilization and membrane damage

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Fig 1

PDIM transport to the outer mycomembrane is required for optimal phagosomal permeabilization by <italic>M</italic>. <italic>marinum</italic>.

Representative dot plots of (A) wildtype, (B) ΔESX-1, and (C) ΔmmpL7 infected THP-1 macrophages 24 hours post infection with overlays of uninfected (blue) and infected (red) cells within each sample. Gating outlined in black, % permeabilization is as labeled. Plots are representative of two independent experiments. (D) Quantification of permeabilization events. Each point represents an independent experiment, symbols indicate matched experiments.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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