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Fig 1

ID

ZDB-FIG-200720-1

Publication

Rosenbauer et al., 2020 - Modeling of Wnt-mediated tissue patterning in vertebrate embryogenesis

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Fig 1

Comparison of cytoneme-based and diffusion-based Wnt transport.

a) and b) show the mean gradient of Wnt concentration (100 simulations) with standard deviation in transparent over the expanding tissue at different times (normalized to the maximum at t = 180 min) with respect to the distance from the embryonic margin, the green area indicates Wnt producing cells. c) and d) show the corresponding 2D cell distribution at the final stage (t = t_TRS = 180 min). Cell fates are determined by thresholds on the local single cell Wnt-concentration. The thresholds are set at t = 180 min so that the cell-numbers in forebrain-, midbrain- and hindbrain-fate are equal. Besides the Wnt producing cells shown in green, the colors of the cells represent different cellular fates: forebrain fate is indicated in red, midbrain fate in white and hindbrain fate in blue.

Expression Data

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Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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