FIGURE

Fig 9

ID

ZDB-FIG-200718-36

Publication

Deveau et al., 2020 - Thyroid hormone receptor beta mutations alter photoreceptor development and function in Danio rerio (zebrafish)

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Fig 9

Irradiance plots: Change in amplitude of arval cone PIII ERG responses as a function of brightness and wavelength.

(A, B) The wild type (N = 17 datasets, 1190 points total) and 6BP+1 heterozygote (N = 16 datasets, 1120 points total) irradiance-amplitude curves are similar at 4 modeled wavelengths, while the 6BP+1 mutant (N = 12 datasets, 840 points total) (C) shows a loss of response to 650 nm that does not change even at higher irradiance levels. (D-F) Wild type (same as in A), 3BP heterozygote (N = 33 datasets, 2310 points total), and 3BP mutant (N = 17 datasets, 1190 points total) larvae are similar in their respective irradiance plots.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	thrb^nds2/nds2 thrb^nds3/nds3 thrb^nds2/+ thrb^nds3/+
Observed In:	retina response to red light
Stage:	Day 5

Phenotype Detail

Acknowledgments

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