FIGURE

Fig. 2

ID

ZDB-FIG-200615-31

Publication

Blume et al., 2020 - Microglia in the developing retina couple phagocytosis with the progression of apoptosis via P2RY12 signaling

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Fig. 2

Accumulation of TUNEL+ cells in the retina when primitive microglia are depleted. Whole embryos were collected and processed for TUNEL (red) staining then DAPI (cyan) counterstaining. Images show selected z projections of whole eyes from mpeg1 :nfsBeYFP embryos treated with DMSO, (A, A?), or Mtz, (B, B?). Orientation is indicated by the compass on bottom left of panel A, N = nasal, V = ventral, D = dorsal (applies to A?B?). The lens and boundary of the eye are indicated by white dashed outlines. C, The total number of TUNEL+ cells per eye was quantified for each indicated group. Box plots are shown for each group with each individual data point shown in red circles. A Welch's one?way test (P = 7.27?�?10?7) was performed, followed by Bonferroni post hoc test. P values shown for pairwise comparison with P ?

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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