FIGURE

Fig. 5

ID

ZDB-FIG-200604-16

Publication

Budine et al., 2020 - Gon4l/Udu Regulates Cardiomyocyte Proliferation and Maintenance of Ventricular Chamber Identity During Zebrafish Development

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Fig. 5

udu genetically interacts with nkx2.5 to maintain ventricular identity. Confocal immunofluorescence images of ventral views of WT (A), udu−/− (B), nkx2.5−/− (C), and udu−/−; nkx2.5−/−(D) zebrafish hearts at 48 hpf with showing the myocardium (MF20, blue) and atrium, (S46, green), and nuclei of cardiomyocytes (Mef2, red). Proportion of total cardiomyocytes with ventricular identity at 48 hpf in WT (grey), udu−/−;nkx2.5+/+ (blue) udu+/+;nkx2.5−/− (red) and udu−/−;nkx2.5−/− (purple) embryos (E). ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001, ∗∗∗∗p < 0.0001, error bars = SEM. Scale bars represent 50 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 462(2), Budine, T.E., de Sena-Tomás, C., Williams, M.L.K., Sepich, D.S., Targoff, K.L., Solnica-Kreze, L., Gon4l/Udu Regulates Cardiomyocyte Proliferation and Maintenance of Ventricular Chamber Identity During Zebrafish Development, 223-234, Copyright (2020) with permission from Elsevier. Full text @ Dev. Biol.