FIGURE

Fig. 2

ID

ZDB-FIG-200416-1

Publication

Wu et al., 2020 - Disruption of dmrt1 rescues the all-male phenotype of cyp19a1a mutant in zebrafish - A Novel insight into the roles of aromatase/estrogens in gonadal differentiation and early folliculogenesis

Other Figures

All Figure Page

Back to All Figure Page

Fig. 2

Phenotype analysis of female zebrafish in different genotypes. (A,B) Histological examination of gonads in different genotypes of dmrt1;cyp19a1a at 75 dpf (A) and 100 dpf (B). PG, primary growth; PV, pre-vitellogenic; EV, early vitellogenic; FG, full grown. Arrows indicate atresic/degenerating follicles. Asterisks indicate stromal cells. (C,D) Ratios of PG, PV and vitellogenic (EV+) follicle areas in different genotypes at 75 dpf (C) and 100 dpf (D). Data are mean±s.d. The exact values are shown under the x-axis. (E) The size of PV follicles in controls and double mutants (dmrt1−/−;cyp19a1a−/−) at 100 dpf. Each dot represents the average diameter of PV follicles with visible germinal vesicles from each fish (quantified from three different sections). Data are mean±s.d. and the exact values are shown under the x-axis. Statistical significance was revealed by two-tailed unpaired Student's t-test (**P<0.01).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	cyp19a1a^umo5/umo5; dmrt1^umo15/umo15 (AB)
Observed In:	ovarian follicle stage II ovarian follicle stage III ovarian follicle stage IV
Stage Range:	Days 45-89 to Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development