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ZFIN ID: ZDB-FIG-200228-59
Riché et al., 2018 - Glycine decarboxylase deficiency-induced motor dysfunction in zebrafish is rescued by counterbalancing glycine synaptic level. JCI insight   3(21) Full text @ JCI Insight
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Antibodies:
Fish:
Anatomical Terms:
Stage Range: Prim-5 to Days 7-13
PHENOTYPE:
Fish:
Observed In:
Stage Range: Prim-5 to Days 7-13

Fig. 6 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
DsRed nns9Tg standard conditions Days 7-13 brain glutamatergic neuron IFL
nns9Tg ; gldcudm301/udm301 standard conditions Days 7-13 brain glutamatergic neuron IFL
GFP gldcudm301/udm301 ; rw0Tg standard conditions Protruding-mouth branchiomotor neuron IFL
ot1Tg standard conditions Days 7-13 brain GABAergic neuron IFL
ot1Tg ; gldcudm301/udm301 standard conditions Days 7-13 brain GABAergic neuron IFL
rw0Tg standard conditions Protruding-mouth branchiomotor neuron IFL
Antibody Labeling Details
Antibody Assay Fish Conditions Stage Anatomy
Ab1-pvalb7 IHC WT standard conditions Day 5 Purkinje cell
IHC gldcudm301/udm301 standard conditions Day 5 Purkinje cell
Ab1-slc17a7 IHC WT standard conditions Day 5 cerebellar granule cell
IHC gldcudm301/udm301 standard conditions Day 5 cerebellar granule cell
Ab1-tuba IHC WT standard conditions Prim-5 brain axon
IHC Day 4 brain axon
IHC gldcudm301/udm301 standard conditions Prim-5 brain axon
IHC Day 4 brain axon
Ab3-th IHC WT standard conditions Day 5 brain dopaminergic neuron
IHC gldcudm301/udm301 standard conditions Day 5 brain dopaminergic neuron
Phenotype Details
Fish Conditions Stage Phenotype
gldcudm301/udm301 standard conditions Prim-5 brain central nervous system projection neuron axonogenesis normal occurrence, normal
Prim-5 brain neural precursor cell proliferation decreased occurrence, abnormal
Protruding-mouth brain neural precursor cell proliferation decreased occurrence, abnormal
Day 4 brain central nervous system projection neuron axonogenesis normal occurrence, normal
Day 5 brain dopaminergic neuron differentiation normal occurrence, normal
Day 5 cerebellum development normal occurrence, normal
Day 5 cerebellum has normal numbers of parts of type Purkinje cell, normal
Days 7-13 brain neural precursor cell proliferation normal occurrence, normal
gldcudm301/udm301 ; rw0Tg standard conditions Protruding-mouth facial ganglion branchiomotor neuron normal position, normal
Protruding-mouth trigeminal ganglion branchiomotor neuron normal position, normal
Protruding-mouth vagal ganglion branchiomotor neuron normal position, normal
nns9Tg ; gldcudm301/udm301 standard conditions Days 7-13 brain glutamatergic neuron differentiation normal occurrence, normal
ot1Tg ; gldcudm301/udm301 standard conditions Days 7-13 brain GABAergic neuron differentiation normal occurrence, normal
Days 7-13 brain has normal numbers of parts of type GABAergic neuron, normal
Full text @ JCI Insight