FIGURE

Fig 10

ID

ZDB-FIG-191230-953

Publication

Serrano et al., 2019 - Inhibition of Notch signaling rescues cardiovascular development in Kabuki Syndrome

Other Figures

Fig 1
Fig 2
Fig 3
Fig 4
Fig 5
Fig 6
Fig 7
Fig 8
Fig 9
Fig 10

(all 10)

All Figure Page

Back to All Figure Page

Fig 10

Model summary schematic.

Schematic cartoon highlighting cardiovascular defects in our genetic zebrafish model for Kabuki Syndrome. Notch signaling is identified as primary candidate pathway underlying the endothelial/endocardial phenotype. Pharmacological inhibition of Notch signaling was able to rescue the cardiovascular phenotype in KS mutants. AA, aortic arch; AV, atrioventricular.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS Biol.