FIGURE

Fig 10

ID

ZDB-FIG-191230-953

Publication

Serrano et al., 2019 - Inhibition of Notch signaling rescues cardiovascular development in Kabuki Syndrome

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Fig 10

Model summary schematic.

Schematic cartoon highlighting cardiovascular defects in our genetic zebrafish model for Kabuki Syndrome. Notch signaling is identified as primary candidate pathway underlying the endothelial/endocardial phenotype. Pharmacological inhibition of Notch signaling was able to rescue the cardiovascular phenotype in KS mutants. AA, aortic arch; AV, atrioventricular.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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