FIGURE

Figure 2

ID

ZDB-FIG-191230-166

Publication

Molagoda et al., 2019 - Fermented Oyster Extract Promotes Osteoblast Differentiation by Activating the Wnt/β-Catenin Signaling Pathway, Leading to Bone Formation

Other Figures

All Figure Page

Back to All Figure Page

Figure 2

FO upregulates the specific marker gene expression responsible for osteoblast differentiation in MC3T3-E1 cells. (A) MC3T3-E1 cells were treated with 100 µg/mL of FO and 100 nM DEX for 7 days. The expression of mRUNX2, mALP, mCol1a1, mOCN, mOSX, mBMP2, and mBMP4 was measured on day 1 (D1), day 3 (D3), day 5 (D5), and day 7 (D7). (B) The cells were also treated with 50 µg/mL and 100 µg/mL of FO or 100 nM DEX for 5 days. The expression of mRUNX2, mALP, mCol1a1, mOCN, mOSX, mBMP2, and mBMP4, was observed. mGAPDH was used as a house keeping gene. Significant differences among the groups were determined using the one-way ANOVA followed by Bonferroni correction. All data are presented as mean ± SEM (*** p < 0.001, ** p < 0.01, and * p < 0.05 versus untreated group). FO; fermented extract of C. gigas and DEX; dexamethasone.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Biomolecules