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Figure 4

ID

ZDB-FIG-191230-1576

Publication

Johansson et al., 2019 - Dkk1 Controls Cell-Cell Interaction through Regulation of Non-nuclear β-Catenin Pools

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Figure 4

Dkk1 Impacts Cell Shape and Orientation

(A) Axial cell angles were measured in dorsally oriented tail bud stage Tg(gsc:GFP) embryos (green axis) expressing membrane mCherryCAAX (red) in control embryos (n = 6,227 cells) and embryos injected with Dkk1 RNA (n = 6,176 cells). ^∗p < 0.05. Scale bar, 20 μm.

(B) Dkk1-RNA-injected embryos (n = 6,176 cells) are less elongated and have a larger cell area than control embryos (n = 6,227 cells). Aspect ratio and cell area were quantified in Tg(gsc:GFP) embryos in (A) expressing membrane mCherry. ^∗∗∗p < 0.001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Cell, 51(6), Johansson, M., Giger, F.A., Fielding, T., Houart, C., Dkk1 Controls Cell-Cell Interaction through Regulation of Non-nuclear β-Catenin Pools, 775-786.e3, Copyright (2019) with permission from Elsevier. Full text @ Dev. Cell