FIGURE

Figure 7

ID

ZDB-FIG-191230-1228

Publication

Jin et al., 2019 - Zebrafish TRIM25 Promotes Innate Immune Response to RGNNV Infection by Targeting 2CARD and RD Regions of RIG-I for K63-Linked Ubiquitination

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Figure 7

A schematic model of zbTRIM25-mediated RLR signaling pathway during RGNNV infection. zbTRIM25 interacts with and catalyzes the K63 polyubiquitination of 2CARD and RD regions of zbRIG-I, which subsequently induces the activation of downstream signaling event via MAVS, and thereby inhibits viral infection.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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