FIGURE

Fig. S5

ID

ZDB-FIG-191011-5

Publication

Dooley et al., 2019 - The gene regulatory basis of genetic compensation during neural crest induction

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Fig. S5

(A-H) Whole mount in situ analysis of wu:fc46h12 and gch2 as a pigment cell comparison. sox10^baz/+ heterozygotes embryos as sibling controls (A-B) and mutant sox10^baz1embryos at 24 hpf (C-D). At 48 hpf in situs were carried out on albino embryos to serve as wild-type controls (E-F) with arrows indicating the heart and arrow heads the dorsal aorta. A blow up of this region can be found in E’-F’. (G-H) Expression of gch2 and wu:fc46h12 at 48 hpf in sox10^baz1 mutants. I-J Wild-type and MZwu:fc46h12^sa30587 embryos at 36 hpf with oedema around the forming heart (J). (K) Wild-type sibling and mutant akr1b1^sa30579at 4 dpf with mutant larvae presenting a reduction of yellow colour produced by xanthophores. Magnifications indicated with a black box. (L) Wild-type sibling and mutant cax1^sa10712 larvae at 5 dpf. Close ups indicated by black boxes around the head show dull yellow colour and abnormal cell morphology in mutants (arrow head). (M) MZcax1^sa10712phenotype at 19 somite stage.

Expression Data

Genes:	gch2 wu:fc46h12
Fish:	slc45a2^b4/b4 sox10^baz1/baz1 sox10^baz1/+
Anatomical Terms:	dorsal aorta heart trunk ventral region xanthoblast xanthophore
Stage Range:	Prim-5 to Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	akr1b1.1^{sa30579/sa30579} cax1^{sa10712/sa10712} cax1^{sa10712/sa10712} sox10^baz1/baz1 wu:fc46h12^{sa30572/sa30572}
Observed In:	dorsal aorta heart trunk ventral region whole organism xanthophore
Stage Range:	14-19 somites to Day 5

Phenotype Detail

Acknowledgments

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