FIGURE

Fig. 3

ID

ZDB-FIG-190829-5

Publication

Umali et al., 2019 - Loss of foxc1 in zebrafish reduces optic nerve size and cell number in the ganglion cell layer

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Fig. 3

Loss of foxc1 function reduced optic nerve thickness. foxc1a morpholino injection into a foxc1b -/- background reduced optic nerve thickness (D) when compared to wildtype embryos injected with standard negative control morpholinos (A), wildtype embryos injected with foxc1a morpholinos (B), foxc1b mutants injected with control morpholinos (C) This is statistically significant (E, comparison of A–D, p = 0.03 (C). Data presented as mean ± SEM. Red line indicates area of measurement. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	foxc1b^{ua1018/ua1018} (AB) AB + MO2-foxc1a foxc1b^{ua1018/ua1018} + MO2-foxc1a (AB)
Knockdown Reagent:	MO2-foxc1a
Observed In:	cranial nerve II
Stage:	Day 5

Phenotype Detail

Acknowledgments

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Reprinted from Vision Research, 156, Umali, J., Hawkey-Noble, A., French, C.R., Loss of foxc1 in zebrafish reduces optic nerve size and cell number in the ganglion cell layer, 66-72, Copyright (2019) with permission from Elsevier. Full text @ Vision Res.