FIGURE
Fig. S2
- ID
- ZDB-FIG-190820-23
- Publication
- Adler et al., 2019 - Clostridium perfringens Epsilon Toxin Compromises the Blood-Brain Barrier in a Humanized Zebrafish Model
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Fig. S2
ETX antibody neutralization eliminates dextran leakage and vascular pathology in hMALGFP expressing fish. Related to Figure 7. (A) 40X confocal images of hMAL-GFP expressing neurovasculature (green) co-injected with 2,000 kDa Dextran (red) and neutralized ETX at 15MPI, 1 HPI, and 2HPI. First three columns represent 3-D volumes depicted in “Merge Macro” blue box. Scale bars= 30µm in first three columns and 50µm in “Merge Macro” column. (B) Example of 2HPI Imaris 3-d rendering of hMAL-GFP and Dextran surfaces. (C) hMAL-GFP expression and DIC confocal imaging of CCtA vessel at the three time points. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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