FIGURE

Fig. 3

ID

ZDB-FIG-190805-30

Publication

Sieber et al., 2019 - Zebrafish as a predictive screening model to assess macrophage clearance of liposomes in vivo

Other Figures

All Figure Page

Back to All Figure Page

Fig. 3

Influence of PEG modification on liposome accumulation in the zebrafish. DiI labeled Liposomes with various PEG molecular weights and PEG densities were injected into blood circulation of zebrafish 2 days post fertilization. (A) The indicated area (dotted box) of injected zebrafish representing part of the caudal vein and the caudal hematopoietic tissue was analyzed for liposome accumulates (white arrows) 24 h post injection. (B) Representative confocal images of the tail region for each liposome formulation are shown. The number of red dots (i.e. liposome accumulates) in the caudal vein was counted and is represented as mean ± SEM (n = 3).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Nanomedicine : nanotechnology, biology, and medicine, 17, Sieber, S., Grossen, P., Uhl, P., Detampel, P., Mier, W., Witzigmann, D., Huwyler, J., Zebrafish as a predictive screening model to assess macrophage clearance of liposomes in vivo, 82-93, Copyright (2019) with permission from Elsevier. Full text @ Nanomedicine