FIGURE

Fig. 1

ID

ZDB-FIG-190723-577

Publication

Li et al., 2019 - STIL: a multi-function protein required for dopaminergic neural proliferation, protection, and regeneration

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Fig. 1

Diagrams that illustrate the roles of STIL in the <italic>Shh</italic> pathway.

a Normally, STIL binds SUFU, releases SUFU’s suppression on GLI1, then GLI1 can be translocated to the nucleus for gene transcription. b When STIL is mutated, Shh down-stream signaling transduction cannot be completed because the SUFU-GLI1 heterodimers cannot enter the nucleus for gene transcription. (Modified from reference¹⁵)

Expression Data

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Antibody Labeling

Phenotype Data

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Acknowledgments

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