IMAGE

Fig. 1

ID
ZDB-IMAGE-190723-620
Source
Figures for Li et al., 2019
Image
Figure Caption

Fig. 1 Diagrams that illustrate the roles of STIL in the <italic>Shh</italic> pathway.

a Normally, STIL binds SUFU, releases SUFU’s suppression on GLI1, then GLI1 can be translocated to the nucleus for gene transcription. b When STIL is mutated, Shh down-stream signaling transduction cannot be completed because the SUFU-GLI1 heterodimers cannot enter the nucleus for gene transcription. (Modified from reference15)

Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Cell Death Discov
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