FIGURE

Fig. 3.

ID

ZDB-FIG-190723-2697

Publication

Ugwuagbo et al., 2019 - Prostaglandin E2 promotes embryonic vascular development and maturation in zebrafish

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Fig. 3.

PGE2 promotes early hatching of zebrafish at 50 hpf. (A–C) Representative images of hatched embryos in non-injected (A), vehicle (B) and PGE2 injected (C) groups. Scale bar: 10 μm. We analyzed n=90 non-injected, n=61 vehicle and n=90 PGE2 embryos. (D) Data are presented as the mean of percentages (hatched/total number of eggs) of hatched embryos±s.e.m. Hatched embryo numbers were significantly high in PGE2 (33%) compared with the vehicle (5%), with a two-tailed unpaired t-test, **P=0.0001. (E) We also recorded the larval movements as a measure of swimming activity post-hatching in all three groups (shown in Movie 2A-C) at 53 hpf. Data presented as the mean of larval movements of hatched embryos [non-injected (n=14), vehicle (n=31) and PGE2 (n=35)]±s.e.m. We conducted an unpaired t-test showing significantly higher motility in PGE2 group compared to the vehicle with a two-tailed unpaired t-test, **P=0.0008.

Expression Data

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Antibody Labeling

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Acknowledgments

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