FIGURE

Fig 3

ID

ZDB-FIG-190723-1664

Publication

Zhou et al., 2018 - Distinct amino acid motifs carrying multiple positive charges regulate membrane targeting of dysferlin and MG53

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Fig 3

Mutation K279A leads to mislocalization of MG53.

(A) Domain structure of the fusion protein turboGFP:MG53. (B) Cellular localization of (top to bottom) turboGFP:MG53 and mutants K278A, R282A, K278A/R282A, K279A, K278A/K279A in HeLa cells. Three representative images are shown for each variant, all imaged with excitation at 488 nm. Scale bars, 10 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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