FIGURE

Fig 4

ID

ZDB-FIG-190723-1476

Publication

Oppel et al., 2019 - Loss of atrx cooperates with p53-deficiency to promote the development of sarcomas and other malignancies

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Fig 4

Histology of tumor types detected in <italic>atrx</italic>+/- zebrafish with <italic>p53/nf1</italic>-deficient background.

This figure shows HE-stained sections of all tumor types detected in p53-/-, nf1b-/-, nf1a+/-, atrx+/- or p53-/-, nf1b-/-, nf1a+/+, atrx+/- fish that were not observed in atrx-wildtype siblings; scale bars: 50μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	tp53^zdf1/zdf1; atrx^zdf37/+; nf1b^p303/p303 tp53^zdf1/zdf1; atrx^zdf37/+; nf1a^p301/+; nf1b^p303/p303
Observed In:	whole organism whole organism neoplasm
Stage:	Adult

Phenotype Detail

Acknowledgments

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