FIGURE

Fig. 5

ID

ZDB-FIG-190716-9

Publication

Wu et al., 2019 - Liposome-Mediated Drug Delivery in Larval Zebrafish to Manipulate Macrophage Function

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Fig. 5

Liposomal etomoxir and MitoTEMPO suppress neutrophil recruitment to injected MSU crystals. (A) Immunofluorescence detection of neutrophils within the hindbrain of Tg(lyz:EGFP) larvae co-injected with MSU crystals and L-PBS, L-Eto, or L-MT, as detected at 3 and 6 hpi, compared with MSU crystal-injected larvae immersed in concentration-matched FD, with corresponding DMSO-treated controls. (B) Temporal quantification of neutrophils within the hindbrain, as detected in (B), n = 13–15 larvae/treatment. All views anterior to left. Error bars display mean ± SD. ****p < 0.0001, one-way ANOVA, Dunnett's post hoc test. Scale bar, 50 μm in (A). FD, free drug.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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