FIGURE

Fig. 6

ID

ZDB-FIG-190627-45

Publication

Carreño Gutiérrez et al., 2019 - Endothelin neurotransmitter signalling controls zebrafish social behaviour

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Fig. 6

Altered distribution of arginine vasopressin neurons in ednraa^−/−. In situ hybridisation showing that expression of arginine vasopressin (avp) is similar in the brain of WT (a,c,e) and ednraa^−/− (b,d,f) at 6 days (a,b) and 12 days (c,d). (e,f) Reduced expression of avp in the ventral parvocellular preoptic area of ednraa^−/− of adult fish. (g,h) In situ hybridisation showing that oxytocin (oxt) expression is similar in WT and ednraa^−/− adult fish. (i,j) Anti-AVP antibody staining shows reduced labelling in the parvocellular preoptic area of ednraa^−/− (j) compared to WT (i) (arrowheads). Dorsal magnocellular neurons have a larger cell body and thicker projections. (k) Reduced levels of AVP in the brain of ednraa^−/− compared to WT. (l) Decreased whole-body cortisol levels in ednraa^−/− compared to WT. *p < 0.05, ***p < 0.001.

Expression Data

Genes:	avp oxt
Fish:	AB ednraa^tj262/tj262 (AB)
Anatomical Terms:	parvocellular preoptic nucleus preoptic area
Stage Range:	Day 6 to Adult

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	ednraa^tj262/tj262 (AB)
Observed In:	brain vasopressin magnocellular preoptic nucleus axon magnocellular preoptic nucleus cell body parvocellular preoptic nucleus whole organism vasopressin
Stage:	Adult

Phenotype Detail

Acknowledgments

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