FIGURE

Fig. 7

ID

ZDB-FIG-190403-7

Publication

Verbueken et al., 2018 - From mRNA Expression of Drug Disposition Genes to In Vivo Assessment of CYP-Mediated Biotransformation during Zebrafish Embryonic and Larval Development

Other Figures

All Figure Page

Back to All Figure Page

Fig. 7

Description of region of interest used for the quantitative and qualitative analysis of resorufin formation in zebrafish embryos and larvae at 7 h post-fertilization (hpf) (a), 26 hpf (b,c), 50 hpf (d,e), 74 hpf (f,g), 98 hpf (h,i), 122 hpf (j,k), 9 d post-fertilization (dpf) (l,m) and 14 dpf (n,o) after exposure to benzyloxy-methyl-resorufin (BOMR) or 7-ethoxyresorufin (ER). The yellow frame indicates the region of interest in the embryo or larva. Since for most embryos/larvae the complete trunk region did not fit within one image, pictures of anterior and posterior trunk were taken separately. For the quantitative analysis of resorufin formation in each embryo/larva, average pixel intensities of anterior and posterior trunk images were combined. Figure 7 (a) shows a vegetal pole view of the embryo. In Figure 7 (b–o) lateral views of the anterior and posterior part of the trunk region are shown. Scale bar: 200 µm; (b,c): anterior top and dorsal right; (d–o): anterior left and dorsal top.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Mol. Sci.