FIGURE

Fig. S2

ID

ZDB-FIG-181002-22

Publication

Powell et al., 2018 - Cxcr1 mediates recruitment of neutrophils and supports proliferation of tumor-initiating astrocytes in vivo

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Fig. S2

Cxcr1/2 inhibition with neutrophil-specific motility loss. Tg(mpx:mCherry-2a-Rac2WT) or Tg(mpx:mCherry-2a-Rac2D57N) embryos were injected with gfap:GFP-krasG12V and treated with 1?M SB225002 or DMSO control as described in Figure 4. Larvae were fixed at 3 dpf and immunostained for phospho-Histone H3 (A). pH3-GFP double positive cells were quantified by optical section and normalized as above (B, n= 10 Rac2WT + DMSO, 19 Rac2D57N + DMSO, 17 Rac2D57N + SB225002). Data pooled from 2 replicates, *p<0.05.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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