FIGURE

Fig. 1

ID

ZDB-FIG-180917-24

Publication

Svahn et al., 2018 - Nucleo-cytoplasmic transport of TDP-43 studied in real time: impaired microglia function leads to axonal spreading of TDP-43 in degenerating motor neurons

Other Figures

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Fig. 1

Fluorescent primary motor neurons in the zebrafish spinal cord at 3 dpf. a Maximum intensity projection of a z-stack of a motor neuron revealing the complete axonal arbour (yellow) projecting into and around the myotome (not shown). At the cell body the spindly dendritic arbour can also be observed. The nucleus is visualised in mCerulean3 (cyan). Traversing the image is the axon of a spinal interneuron. Scale = 10 µm. b A separate fluorescent motor neuron (bi), demonstrating the mnx1-driven membrane-bound mKO2-CAAX (yellow, bii), nuclear H2B-mCerulean3 (cyan, biii) and HsaTDP43^WT-linked eGFP (green, biv). Scale = 2 µm

Expression Data

Genes:	Cerulean EGFP mKOFP2
Fish:	mq13Tg; mq14Tg
Anatomical Terms:	primary motor neuron axon primary motor neuron dendrite primary motor neuron membrane primary motor neuron nucleus
Stage:	Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Acta Neuropathol.