FIGURE

Fig. 4

ID

ZDB-FIG-180910-32

Publication

Chi et al., 2018 - Loss of runx1 function results in B cell immunodeficiency but not T cell in adult zebrafish.

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Fig. 4

Cell-autonomous regulation of runx1 in B cells development. (a) Schematic outline showing procedure of transplantation. (b) Macroscopic representation of kidney marrow of donors (top), donors after irradiation (middle) and hosts reconstituted with donors kidney morrow (below, 4 weeks after transplantation). Ovals indicate the locations of the head kidneys; dpt, day post transplantation; scales bars, 5 mm. (c) Fluorescent representation of igm:eGFP⁺ from reconstituted kidney morrow of hosts (4 weeks after transplantation). Scales bars, 100 µm. (d) Percentage of igm:eGFP⁺ in lymphocytes from reconstituted hosts kidney marrow were calculated by FACS analysis. Each experiment was performed in duplicate. Black boxes outline the captured igm:eGFP⁺ cells with fluorescence in lymphocytes region of kidney marrow.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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