FIGURE

Fig. S1

ID

ZDB-FIG-180730-45

Publication

Juan et al., 2018 - Myosin1D is an evolutionarily conserved regulator of animal left-right asymmetry

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Fig. S1

Genetic inactivation of zebrafish myo1D a, Sequence chromatograms and schematic representation of myo1D mutants generated by Crispr/Cas9 mutagenesis. b, myo1D homozygous mutant adult fish are indistinguishable from heterozygous or homozygous wild-type siblings. c, Whole-mount in situ hybridization reveals that myo1D transcripts are maternally supplied and can be detected at the 8-cell stage (animal pole view), well before the activation of the zygotic genome. d, e, Zygotic myo1D transcripts are present at low levels throughout the embryo. At segmentation stages, increased transcript levels are detected in the notochord. d, dorsal view, anterior up. e, lateral view, anterior to the left. Scale bars: 100 μm.

Expression Data

Gene:	myo1d
Fish:	WT
Anatomical Terms:	notochord whole organism
Stage Range:	8-cell to 20-25 somites

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	myo1d^{nce16b/nce16b} myo1d^nce16b/+
Observed In:	whole organism
Stage:	Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Nat. Commun.