Fig. 4
- ID
- ZDB-FIG-180511-37
- Publication
- Berger et al., 2018 - In Vivo Function of the Chaperonin TRiC in α-Actin Folding during Sarcomere Assembly
- Other Figures
- (all 10)
- All Figure Page
- Back to All Figure Page
All cct Mutants Show Retina Degeneration, Except for cct5tf212b (A) H&E-stained sections of 3-dpf-old cct3sa1761 mutants showed severe retina degeneration (n = 11 per genotype) accompanied by abundant apoptosis detected by TUNEL assay (n = 6 per genotype). (B) At 3 dpf, retina degeneration was also apparent on H&E-stained sections of the insertion mutant cct5hi2972Tg but not of the missense mutant cct5tf212b (n = 11 per genotype). (C) Pursuant to the retina degeneration, immunohistochemistry with antibodies against acetylated α-tubulin detected neurite defects in the tectum (arrowheads) of cct3sa1761 and cct5hi2972Tg but not cct5tf212b homozygotes (n = 4 per genotype). See also Figure S6. |
Antibody: | |
---|---|
Fish: | |
Anatomical Term: | |
Stage: | Protruding-mouth |
Fish: | |
---|---|
Observed In: | |
Stage: | Protruding-mouth |