FIGURE

Fig. 7

ID

ZDB-FIG-180420-45

Publication

Richter et al., 2017 - Small molecule screen in embryonic zebrafish using modular variations to target segmentation

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Fig. 7

Overview of selected direct segmentation phenotypes. a Schematic of axial distributions of known mutant somite boundary defects (green brackets) and newly identified small molecule perturbation defects (blue brackets, this paper). Her1, integrin α5 [itga5] and fibronectin 1a [fn1a] anterior defects; T-box 6 [tbx6] mutants, defects along axis; mutants deltaD [dld], deltaC [dlc], notch1a, mindbomb E3 ubiquitin protein ligase 1 [mib1] and her7, posterior defects^{11,12,71,72,73,74}. b Schematic highlighting steps of segmentation (clock circuit, pattern translation, somite maturation) in red boxes and examples of small molecules from the screen that affect the corresponding step

Expression Data

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Antibody Labeling

Phenotype Data

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Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Nat. Commun.