ZFIN Image: Richter et al., 2017, Fig. 7

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Figure Caption

Fig. 7

Overview of selected direct segmentation phenotypes. a Schematic of axial distributions of known mutant somite boundary defects (green brackets) and newly identified small molecule perturbation defects (blue brackets, this paper). Her1, integrin α5 [itga5] and fibronectin 1a [fn1a] anterior defects; T-box 6 [tbx6] mutants, defects along axis; mutants deltaD [dld], deltaC [dlc], notch1a, mindbomb E3 ubiquitin protein ligase 1 [mib1] and her7, posterior defects^{11,12,71,72,73,74}. b Schematic highlighting steps of segmentation (clock circuit, pattern translation, somite maturation) in red boxes and examples of small molecules from the screen that affect the corresponding step

Acknowledgments

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