FIGURE

Fig. 1

ID

ZDB-FIG-180418-16

Publication

Sarmah et al., 2017 - Embryonic Ethanol Exposure Affects Early- and Late-Added Cardiac Precursors and Produces Long-Lasting Heart Chamber Defects in Zebrafish

Other Figures

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Fig. 1

Ethanol-induced cardiac chamber defects occurring during embryogenesis persisted in older zebrafish larvae. (A–C) 3D renderings of confocal sections of Tg(kdrl:EGFP) show closely attached atrium and ventricle residing side by side in the control larva (A); ventricles are on the top of the atria in ethanol-exposed larvae (B,C); Dotted yellow line represents the line through AV valves connecting atrium and ventricle. The angle between yellow line and antero-posterior axis is shown by white dots; (D–F) Masson’s trichrome stained histology sections at the atrioventricular canal region showing both atrium and ventricle revealed defective anatomy of the ethanol-exposed larvae (E,F) compared to control (D); (G–I) Masson’s trichrome stained histology sections of the ventricle showed healthy looking cardiac muscle (red colored trabeculae) in control larva (G); and myocardial damage (blue colored trabeculae, yellow arrows) in ethanol-exposed larvae (H,I).

Expression Data

Gene:	GFP
Fish:	la116Tg
Condition:	chemical treatment by environment: ethanol
Anatomical Term:	heart
Stage:	Days 14-20

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT la116Tg
Condition:	chemical treatment by environment: ethanol
Observed In:	atrioventricular valve atrium cardiac ventricle heart trabecular layer Collagen
Stage:	Days 14-20

Phenotype Detail

Acknowledgments

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