FIGURE

Fig. 2

ID

ZDB-FIG-180412-2

Publication

Razaghi et al., 2017 - hace1 influences zebrafish cardiac development via ROS-dependent mechanisms

Other Figures

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Fig. 2

hace1?morphant embryos display specific cardiac phenotypes that can be rescued by human HACE1 mRNA while the vasculature remains intact. A: The looping defect that results from hace1 knockdown results in either misalignment of the atrium and the ventricle (the ventricle is located on the left side [white arrow], ?inverted?) in ii or a tubular heart (?straight') in iii. Scale bar?=?250?�m. B: Diagrammatic representation of each phenotype is included adjacent to a fluorescent image of a Tg(myl7::eGFP) hace1?morphant embryo with the associated phenotype. C: Bar graphs showing the percent of each of the representative anatomic phenotypes shown in panels A and B (colors correspond to the respective phenotypes; n?=?90?130 embryos for each group in 3 replicates; lateral views at 48 hpf; **P??0.05). Scale bar?=?250?�m.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	twu34Tg + MO1-hace1 y1Tg + MO1-hace1
Knockdown Reagent:	MO1-hace1
Observed In:	heart heart contraction vasculature development
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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