FIGURE

Fig. 7

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ZDB-FIG-180105-9
Publication
Saarenpää et al., 2017 - Zebrafish GDNF and its co-receptor GFRα1 activate the human RET receptor and promote the survival of dopaminergic neurons in vitro
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Fig. 7

zGDNF supports the survival of cultured mammalian dopaminergic neurons.

(A) the counted number of embryonic dopaminergic neurons in the presence of zGDNF and hGDNFIC versus negative control (media), (B) immunofluorescent staining of midbrain culture on 5DIV with a marker for DA neurons: TH (red) and nuclear dye DAPI (blue) comparing 0.27 nM of hGDNFIC, zGDNF and no GFL (control). Black bars: zGDNF; red bars: hGDNFIC; white bar: negative control. N = 4 indiviaul experiments per condition; statistically different from control ***p< 0.0007, **p< 0.003, *p<0.03.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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