FIGURE

Fig. 4

ID
ZDB-FIG-171121-12
Publication
Ashikawa et al., 2016 - Activation of Sterol Regulatory Element Binding Factors by Fenofibrate and Gemfibrozil Stimulates Myelination in Zebrafish
Other Figures
All Figure Page
Back to All Figure Page
Fig. 4

Effects of thyroid hormone modulators on mbp promoter-driven fluorescence in zebrafish. (A) Representative images from in vivo analysis of Tg (mbp: mCitrine, eno2: Cerulean) zebrafish incubated with or without the indicated concentrations of methimazole (MMI), propylthiouracil (PTU), or thyroxine (T4). (B) Quantification of mCitrine fluorescence intensity within the area of Cerulean fluorescence. (Top) Zebrafish were untreated (n = 40) or treated with MMI (n = 16 for 0.5 mM, n = 26 for 1 mM, n = 27 for 2 mM). (Middle) Zebrafish were untreated (n = 11) or treated with PTU (n = 5 for 1 mM, n = 10 for 2 mM, n = 3 for 3 mM). (Bottom) Zebrafish were untreated (n = 20) or treated with T4 (n = 6 for 10 nM, n = 5 for 20 nM, n = 9 for 30 nM). ∗∗p < 0.01, ∗∗∗∗p < 0.0001 compared with control.
Expression Data
Genes:
Fish:
Conditions:
Anatomical Terms:
Stage: Day 5

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Conditions:
Observed In:
Stage: Day 5

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Pharmacol
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.