FIGURE

Fig. 2

ID

ZDB-FIG-171110-32

Publication

Sasagawa et al., 2016 - DNA Damage Response Is Involved in the Developmental Toxicity of Mebendazole in Zebrafish Retina

Other Figures

All Figure Page

Back to All Figure Page

Fig. 2

Development during 2 and 3 dpf was the critical window for developmental toxicity of MBZ in the zebrafish retina. (A) Zebrafish were treated with 0.3 μM MBZ during the indicated periods. At 6 dpf, zebrafish were stained with ZMA462 and the retinas were imaged in vivo. The malformations in the IPL caused by MBZ are indicated by yellow arrows. Scale bar: 50 μm. (B) Quantitative analysis of the developmental toxicity of 0.3 μM MBZ in the zebrafish retina. The shape of the IPL in each zebrafish was quantified using the shape factor. n = 5 for control, n = 6 for 1–4 dpf, n = 4 for 2–5 dpf and 3–6 dpf, *p < 0.05 compared with control.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Pharmacol