FIGURE

Fig. 1

ID

ZDB-FIG-171110-31

Publication

Sasagawa et al., 2016 - DNA Damage Response Is Involved in the Developmental Toxicity of Mebendazole in Zebrafish Retina

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Fig. 1

MBZ caused developmental toxicity in the zebrafish retina. (A) Zebrafish were treated with MBZ from 0 to 5 dpf at the indicated concentration. At 5 dpf, zebrafish were stained with ZMA462 and the retinas were imaged in vivo. The GCL, IPL, INL, and OPL are indicated by white arrows. The malformations in the IPL and OPL caused by MBZ are indicated by yellow and blue arrows, respectively. Scale bar: 50 μm. (B) Quantitative analysis of the developmental toxicity of MBZ in the zebrafish retina. The shape of the IPL in each zebrafish were quantified using the shape factor. n = 8 for control, n = 3 for each concentration, *p < 0.05 compared with control.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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