FIGURE

Fig. S1

ID
ZDB-FIG-170706-9
Publication
Wager et al., 2016 - Neurodegeneration and Epilepsy in a Zebrafish Model of CLN3 Disease (Batten Disease)
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Fig. S1

Abnormal morphology was observed using two different cln3 morpholinos at 4 dpf.

(A, A') WT. (B, B') 1.6 ng cln3 ATG MO. (C, C') 12 ng cln3 SPL MO. Morphant larvae (B, B', C, C') showed small retinas, small brain, pericardial oedema, a large yolk sac and abnormal tail curvature (dashed arrows) compared to WT (A, A'). Abbreviations: r, retina; ps, pericardial sac; y, yolk; t, tail; fb, forebrain; mb, midbrain; hb, hindbrain. Lateral views. Anterior to left. Dorsal up. Scale bars: A-C 250 μm; A'-C' 125 μm.
Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Knockdown Reagent:
Observed In:
Stage: Day 4

Phenotype Detail
Acknowledgments
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