FIGURE

Fig. 3

ID

ZDB-FIG-170605-23

Publication

Zang et al., 2017 - Development of a Novel Zebrafish Model for Type 2 Diabetes Mellitus

Other Figures

All Figure Page

Back to All Figure Page

Fig. 3

Increased insulin production in DIO zebrafish. (a) Fasting blood glucose concentrations of ins-EGFP zebrafish after 3 months of normal feeding or overfeeding. n = 10. (b) Insulin-EGFP signals in exocrine pancreas were monitored in non-DIO and DIO ins-EGFP zebrafish by fluorescence stereoscopic microscopy. Scale bar = 0.5 mm. (c) Graph of the percentage of EGFP positive signal area in entire image. n = 3. (d) Graph of relative EGFP intensities from panel b. n = 3. (e) Western blot analysis for GFP signals in liver-pancreas tissue of non-DIO and DIO ins-EGFP. Full-length blots are presented in Supplementary Fig. S3. Values are means ± SE. *P < 0.05, **P < 0.01 vs. the non-DIO group.

Expression Data

Gene:	EGFP
Fish:	sc1Tg
Condition:	increased food availability
Anatomical Terms:	exocrine pancreas pleuroperitoneal cavity
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	sc1Tg
Condition:	increased food availability
Observed In:	blood glucose exocrine pancreas pleuroperitoneal cavity
Stage:	Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Sci. Rep.