FIGURE

Fig. 3

ID

ZDB-FIG-170605-23

Publication

Zang et al., 2017 - Development of a Novel Zebrafish Model for Type 2 Diabetes Mellitus

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Fig. 3

Increased insulin production in DIO zebrafish. (a) Fasting blood glucose concentrations of ins-EGFP zebrafish after 3 months of normal feeding or overfeeding. n?=?10. (b) Insulin-EGFP signals in exocrine pancreas were monitored in non-DIO and DIO ins-EGFP zebrafish by fluorescence stereoscopic microscopy. Scale bar?=?0.5?mm. (c) Graph of the percentage of EGFP positive signal area in entire image. n?=?3. (d) Graph of relative EGFP intensities from panel b. n?=?3. (e) Western blot analysis for GFP signals in liver-pancreas tissue of non-DIO and DIO ins-EGFP. Full-length blots are presented in Supplementary Fig. S3. Values are means?±?SE. *P?<?0.05, **P?<?0.01 vs. the non-DIO group.

Expression Data

Gene:	EGFP
Fish:	sc1Tg
Condition:	increased food availability
Anatomical Terms:	exocrine pancreas pleuroperitoneal cavity
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	sc1Tg
Condition:	increased food availability
Observed In:	blood glucose exocrine pancreas pleuroperitoneal cavity
Stage:	Adult

Phenotype Detail

Acknowledgments

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