ZFIN Image: Zang et al., 2017, Fig. 3

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Figure Caption

Fig. 3

Increased insulin production in DIO zebrafish. (a) Fasting blood glucose concentrations of ins-EGFP zebrafish after 3 months of normal feeding or overfeeding. n?=?10. (b) Insulin-EGFP signals in exocrine pancreas were monitored in non-DIO and DIO ins-EGFP zebrafish by fluorescence stereoscopic microscopy. Scale bar?=?0.5?mm. (c) Graph of the percentage of EGFP positive signal area in entire image. n?=?3. (d) Graph of relative EGFP intensities from panel b. n?=?3. (e) Western blot analysis for GFP signals in liver-pancreas tissue of non-DIO and DIO ins-EGFP. Full-length blots are presented in Supplementary Fig. S3. Values are means?�?SE. *P?<?0.05, **P?<?0.01 vs. the non-DIO group.

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Acknowledgments

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